Guardian and COVID-19
Guardian is being deployed as an intervention for optimizing the care of mechanically-ventilated patients during the COVID-19 pandemic
A 399-patient randomized, controlled trial studying adverse event prevention in high-risk acute care patients, comparing TurnCare to alternating pressure beds:
81% reduction in sacral region pressure injuries
Other systemic benefits observed
Learn more in the Journal of Wound, Ostomy, and Continence Nursing:
Designed by clinicians to prevent sacral region vascular compression and improve outcomes for critical care patients
TurnCare Guardian System named
US Business News Critical Care Product of the Year
Bharucha JB, Seaman L, Powers M, Kelly E, Seaman R, Forcier L, ... & Wang L. A prospective randomized clinical trial of a novel, noninvasive perfusion enhancement system for the prevention of hospital-acquired sacral pressure injuries. Journal of Wound Ostomy & Continence Nursing. 2018;45(4);310-318.
Doll DN, Barr TL, Simpkins JW. Cytokines: Their role in stroke and potential use as biomarkers and therapeutic targets. Aging and Disease. 2014;5(5);294-306.
Eltzschig HK, Eckle T. Ischemia and reperfusion–from mechanism to translation. Nature medicine. 2011;17:1391–1401.
Kalogeris T, Baines CP, Krenz, M, Korthuis, RJ. Cell biology of ischemia/reperfusion injury. Int Rev Cell Mol Biol. 2012;298;229-317.
Needham DM. Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function. JAMA. 2008;300:1685–1690.
Parker A, Sricharoenchai T, Needham DM. Early rehabilitation in the intensive care unit: preventing physical and mental health impairments. Curr Phys Med Rehabil Rep. 2013;1(4):307–314.
Payen D, Lukaszewicz AC, Legrand M, Gayat E, Faiyre V, et al. A multicentre study of acute kidney injury in severe sepsis and septic shock: Association with inflammatory phenotype and HLA genotype. PLos ONE. 2012;7(6);e35838.
Pierce SM, Skalak TC, Rodeheaver GT. Ischemia-reperfusion injury in chronic pressure ulcer formation: a skin model in the rat. Wound Repair and Regeneration. 2000;8(1);68-76.
Truong A, Fan E, Brower R, Needham D. Bench-to-bedside review: mobilizing patients in the intensive care unit—from pathophysiology to clinical trials. Crit Care. 2009;13:216.
Zhang JM, An J. Cytokines, inflammation, and pain. International anesthesiology clinics. 2007;45(2);27-37.